Description

9-(4-Phenylpiperazin-1-yl)-1,2,3,4-tetrahydroacridine is a sophisticated heterocyclic compound featuring a fused acridine-piperazine structure. This molecular architecture makes it a valuable advanced pharmaceutical intermediate and a key scaffold in medicinal chemistry research. It is primarily utilized by R&D organizations and fine chemical manufacturers engaged in the development of novel therapeutic agents, particularly for central nervous system (CNS) targets.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates targeting neurological disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Acetylcholinesterase (AChE) Inhibitor Development: Acts as a precursor for compounds being investigated for cognitive enhancement and Alzheimer's disease treatment.
• Ligand Synthesis for Receptor Studies: Employed in creating specific ligands for serotonin and dopamine receptor research.
• Fine Chemical Synthesis: Used in multi-step organic synthesis for producing complex, high-value specialty chemicals.

Basic Information

Product Name	9-(4-Phenylpiperazin-1-yl)-1,2,3,4-tetrahydroacridine
CAS No.	7032-39-5
Molecular Formula	C23H25N3
Molecular Weight	343.47 g/mol
Synonyms	9-(4-Phenyl-1-piperazinyl)-1,2,3,4-tetrahydroacridine; 1,2,3,4-Tetrahydro-9-(4-phenyl-1-piperazinyl)acridine; 9-(4-Phenylpiperazino)-1,2,3,4-tetrahydroacridine; TAK-147 Intermediate; Zanapezil Intermediate; N-(4-Phenylpiperazin-1-yl)-1,2,3,4-tetrahydroacridin-9-amine
EINECS	Contact for details

Quality Control

Our production of 9-(4-Phenylpiperazin-1-yl)-1,2,3,4-tetrahydroacridine adheres to stringent quality protocols suitable for research and pharmaceutical intermediate applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure identity, potency, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.