Description

Cucurbitacin H is a highly bioactive triterpenoid compound belonging to the cucurbitacin family, known for its potent pharmacological properties. This compound is of significant interest for its role as a key research standard in the study of natural product chemistry and its potential therapeutic applications. It is primarily sought after by research institutions, pharmaceutical developers, and biotechnology companies engaged in drug discovery and biochemical research. The compound is supplied with a focus on high purity and batch-to-batch consistency to ensure reliable experimental results.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and active pharmaceutical ingredient (API) intermediate in the investigation of anti-cancer, anti-inflammatory, and hepatoprotective agents.
• Biochemical Studies: Used as a specific molecular probe to study cellular signaling pathways, particularly those involving STAT3 and JAK-STAT inhibition.
• Natural Product Isolation & Analysis: Acts as a key analytical standard for the identification, quantification, and purity assessment of cucurbitacin compounds in plant extracts and herbal formulations.
• Academic Research: Employed in university and institutional labs for pharmacological screening, structure-activity relationship (SAR) studies, and mechanistic biology research.
• Preclinical Development: Utilized in in vitro and in vivo studies to evaluate efficacy, pharmacokinetics, and toxicology profiles for potential new drug candidates.

Basic Information

Product Name	Cucurbitacin H
CAS No.	751-95-1
Molecular Formula	C₃₂H₄₈O₈
Molecular Weight	560.73 g/mol
Synonyms	23,24-Dihydrocucurbitacin F; Dihydrocucurbitacin F; Cucurbitacin H (23,24-Dihydrocucurbitacin F); 2β,16α,20(R),25-Tetrahydroxy-9β-methyl-19-norlanosta-5,23-diene-3,11,22-trione; Elatericin B
EINECS	Contact for details

Quality Control

Our Cucurbitacin H is manufactured under strict quality management protocols. Each batch is subjected to comprehensive analytical testing including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research-grade standards. Our quality system is designed to meet the stringent requirements of pharmaceutical and advanced research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at 2-8°C. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.