Description

Piperazine, 1-[[3-(4-Fluorophenyl)-1H-Pyrazol-4-Yl]Methyl]-4-[4-(Trifluoromethyl)-2-Pyridinyl]- is a high-value, fluorinated piperazine derivative designed for advanced pharmaceutical research and development. This compound matters as a sophisticated chemical building block for creating novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular interactions. Pharmaceutical companies, agrochemical R&D teams, and advanced material scientists need this precise intermediate to develop next-generation drugs and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel small-molecule drugs, particularly for central nervous system (CNS) and oncology targets.
• Kinase Inhibitor Research: Serves as a core scaffold for designing and synthesizing potential kinase inhibitors due to its pyridine and pyrazole motifs.
• Agrochemical Active Ingredient Development: Used in the research phase for creating new crop protection agents with enhanced efficacy.
• Chemical Biology Probe Synthesis: Employed in academic and industrial labs to create molecular probes for studying biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Fluorinated Compound Library Building: An important member for combinatorial chemistry libraries focusing on fluorinated compounds, which are prized for their metabolic stability and membrane permeability.

Basic Information

Item	Details
Product Name	Piperazine, 1-[[3-(4-Fluorophenyl)-1H-Pyrazol-4-Yl]Methyl]-4-[4-(Trifluoromethyl)-2-Pyridinyl]-
CAS No.	696585-94-1
Molecular Formula	C21H19F4N5
Molecular Weight	417.41 g/mol
Synonyms	1-{[3-(4-Fluorophenyl)-1H-pyrazol-4-yl]methyl}-4-[4-(trifluoromethyl)pyridin-2-yl]piperazine; 4-[4-(Trifluoromethyl)-2-pyridinyl]-1-[[3-(4-fluorophenyl)-1H-pyrazol-4-yl]methyl]piperazine; 696585-94-1; 1-((3-(4-Fluorophenyl)-1H-pyrazol-4-yl)methyl)-4-(4-(trifluoromethyl)pyridin-2-yl)piperazine
EINECS	Contact for details

Quality Control

Every batch of our Piperazine derivative is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and mass spectrometry is supplied with each shipment. Our quality commitment aligns with cGMP principles where applicable for non-clinical use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.