Description

1-Methyl-4-[[4-Nitro-2-(Trifluoromethyl)Phenyl]Methyl]-Piperazine is a specialized piperazine derivative featuring a nitro and trifluoromethyl substituted aromatic ring, making it a valuable advanced intermediate for pharmaceutical and agrochemical research. This compound is critical for the synthesis of novel active ingredients, particularly in the development of targeted small molecule therapies. Its unique structure is sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecules with specific biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research pipelines.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl and nitro functional groups.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and receptor interactions in biological systems.
• Material Science Precursor: Potential intermediate for synthesizing specialty polymers or ligands for catalysts used in fine chemical manufacturing.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of complex active pharmaceutical ingredients (APIs).

Basic Information

Product Name	1-Methyl-4-[[4-Nitro-2-(Trifluoromethyl)Phenyl]Methyl]-Piperazine
CAS No.	694499-24-6
Molecular Formula	C13H16F3N3O2
Molecular Weight	303.28 g/mol
Synonyms	1-Methyl-4-[(4-nitro-2-(trifluoromethyl)phenyl)methyl]piperazine; 4-Nitro-2-(trifluoromethyl)benzyl 1-Methylpiperazine; 1-Methyl-4-((4-nitro-2-(trifluoromethyl)benzyl))piperazine; N-Methyl-4-((4-nitro-2-(trifluoromethyl)benzyl))piperazine; 694499-24-6; 1-Methyl-4-[[4-nitro-2-(trifluoromethyl)phenyl]methyl]piperazine
EINECS	Contact for details

Quality Control

Our 1-Methyl-4-[[4-Nitro-2-(Trifluoromethyl)Phenyl]Methyl]-Piperazine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber glass, or stored in dark conditions.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.