Description

Bicyclo[2.2.1]Hept-5-Ene-2-Methanol, 2-(Trifluoromethyl)- (9Ci) is a specialized, high-value bicyclic organic compound featuring a reactive norbornene core and a trifluoromethyl-substituted methanol side chain. This unique structure makes it a critical advanced pharmaceutical intermediate (API) and a versatile building block for synthesizing complex molecules with tailored properties. It is essential for R&D and production in pharmaceutical discovery, agrochemicals, and advanced material science, where its rigid scaffold and fluorine content are leveraged to modulate bioactivity and material characteristics.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory drugs.
• Agrochemical Synthesis: Used as a building block for developing new-generation pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Employed in the development of specialty polymers, resins, and liquid crystals, utilizing its rigid bicyclic structure to influence material rigidity and thermal properties.
• Organic Synthesis & Catalysis: Acts as a sophisticated ligand or substrate in asymmetric catalysis and organic transformation research for academic and industrial laboratories.
• Fluorine Chemistry: A valuable reagent for introducing the trifluoromethyl group into complex molecular architectures, a common strategy in modern medicinal chemistry.

Basic Information

Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Methanol, 2-(Trifluoromethyl)- (9Ci)
CAS No.	693826-78-7
Molecular Formula	C9H11F3O
Molecular Weight	192.18 g/mol
Synonyms	2-(Trifluoromethyl)bicyclo[2.2.1]hept-5-ene-2-methanol; 2-(Trifluoromethyl)-2-norbornenemethanol; 5-Norbornene-2-methanol, 2-(trifluoromethyl)-; 2-(Trifluoromethyl)norborn-5-ene-2-methanol; Bicyclo[2.2.1]hept-5-ene-2-methanol, 2-(trifluoromethyl)-; 2-(Trifluoromethyl)-5-norbornene-2-methanol; Norbornene trifluoromethyl methanol derivative
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Hept-5-Ene-2-Methanol, 2-(Trifluoromethyl)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring GMP-grade intermediates and high-purity research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere or inert gas to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.