Description

5-(4-Carbamoyl-Piperazin-1-Yl)-5-Oxo-Pentanoic Acid is a high-purity, non-natural amino acid derivative featuring a piperazine carboxamide moiety. This compound is a critical pharmaceutical intermediate and research chemical used in the synthesis of novel bioactive molecules. It is primarily required by pharmaceutical R&D and fine chemical synthesis sectors for developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in oncology and CNS research.
• Protease Inhibitor Development: Used in creating novel inhibitors targeting specific enzymatic pathways.
• Peptidomimetic Chemistry: Serves as a constrained scaffold in the design of peptide analogs with enhanced metabolic stability.
• Bioconjugation & Linker Chemistry: The carboxylic acid and amide functionalities enable its use as a versatile linker in antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology Research: Employed as a tool compound or probe to study biological interactions and signaling pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke molecules under cGMP conditions.

Basic Information

Product Name	5-(4-Carbamoyl-Piperazin-1-Yl)-5-Oxo-Pentanoic Acid
CAS No.	693790-16-8
Molecular Formula	C10H17N3O4
Molecular Weight	243.26 g/mol
Synonyms	5-(4-Carbamoylpiperazin-1-yl)-5-oxopentanoic acid; 5-Oxo-5-(4-carbamoylpiperazin-1-yl)pentanoic acid; 4-(4-Carbamoyl-1-piperazinyl)-4-oxobutanoic acid; Pentanoic acid, 5-(4-carbamoyl-1-piperazinyl)-5-oxo-; 693790-16-8; 5-(4-Carbamoylpiperazino)-5-oxovaleric acid; 5-(4-Carbamoylpiperazin-1-yl)-5-oxovaleric acid; 4-Oxo-4-(4-carbamoylpiperazin-1-yl)butyric acid
EINECS	Contact for details

Quality Control

Our 5-(4-Carbamoyl-Piperazin-1-Yl)-5-Oxo-Pentanoic Acid is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided. We support development with custom purity grades and specifications aligned with cGMP principles where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.