Description

4-Piperidinecarboxylic Acid, 1-(4-Bromobenzoyl)- is a high-purity, functionalized piperidine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines a carboxylic acid group with a brominated aromatic moiety on the piperidine nitrogen, enabling precise chemical modifications. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, receptor modulators, and enzyme inhibitors.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides, where the bromophenyl and piperidine groups contribute to biological activity.
• Chemical Synthesis Building Block: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and for introducing specific functional groups into more complex molecules.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.
• Academic and R&D Laboratories: Utilized in fundamental research exploring new organic reactions and heterocyclic chemistry.

Basic Information

Product Name	4-Piperidinecarboxylic Acid, 1-(4-Bromobenzoyl)-
CAS No.	693237-87-5
Molecular Formula	C13H14BrNO3
Molecular Weight	312.16 g/mol
Synonyms	1-(4-Bromobenzoyl)piperidine-4-carboxylic Acid; 4-Piperidinecarboxylic Acid, 1-[(4-Bromophenyl)carbonyl]-; 1-(4-Bromobenzoyl)-4-piperidinecarboxylic Acid; 1-(p-Bromobenzoyl)isonipecotic Acid; Isonipecotic Acid, 1-(4-Bromobenzoyl)-; 4-Carboxy-1-(4-bromobenzoyl)piperidine; N-(4-Bromobenzoyl)isonipecotic Acid
EINECS	Contact for details

Quality Control

Our 4-Piperidinecarboxylic Acid, 1-(4-Bromobenzoyl)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the exacting standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed and under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.