Description

n-[4-(4-Acetylpiperazin-1-Yl)Phenyl]Guanidine is a high-purity, advanced pharmaceutical intermediate characterized by its unique guanidine and acetylpiperazine-substituted phenyl structure. This compound is critical for the research and development of novel therapeutic agents, particularly in the fields of oncology and central nervous system (CNS) disorders. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly kinase inhibitors and receptor modulators.
• Oncology Research: Used in the development of targeted cancer therapies due to its potential role in modulating specific enzymatic pathways.
• CNS Drug Discovery: Applied in research programs focused on neurological and psychiatric conditions, leveraging its structural features for blood-brain barrier penetration.
• Chemical Biology: Acts as a probe or precursor in biochemical assays to study protein-ligand interactions and cellular signaling mechanisms.
• Custom Synthesis: Employed by fine chemical suppliers for the contract manufacturing of bespoke molecules for clinical trials.
• Academic Research: Utilized in university and institutional labs for medicinal chemistry projects and pharmacological studies.

Basic Information

Product Name	n-[4-(4-Acetylpiperazin-1-Yl)Phenyl]Guanidine
CAS No.	693230-06-7
Molecular Formula	C13H19N5O
Molecular Weight	261.33 g/mol
Synonyms	1-[4-(4-Acetyl-1-piperazinyl)phenyl]guanidine; 4-(4-Acetylpiperazin-1-yl)phenylguanidine; Guanidine, N-[4-(4-acetyl-1-piperazinyl)phenyl]-; N-(4-(4-Acetylpiperazin-1-yl)phenyl)guanidine; 693230-06-7; UNII-9J8F9X8V1F; 9J8F9X8V1F; AKOS025310923; AS-69323; FT-0699066; NS00082333
EINECS	Contact for details

Quality Control

Our n-[4-(4-Acetylpiperazin-1-Yl)Phenyl]Guanidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.