Description

4-(Piperazine-1-Carbonyl)-Benzoic Acid is a high-purity organic building block featuring a benzoic acid core linked to a piperazine moiety via a carbonyl group. This bifunctional structure makes it a valuable intermediate for synthesizing complex molecules, particularly in pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the life sciences industry for creating novel active pharmaceutical ingredients (APIs) and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used in the design and construction of compound libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• API Development: Serves as a precursor in the development and scale-up processes for new active pharmaceutical ingredients.
• Bioconjugation & Linker Chemistry: The carboxylic acid and secondary amine functionalities allow for its use as a versatile linker in bioconjugation and the synthesis of antibody-drug conjugates (ADCs).
• Chemical Biology Probes: Useful for creating molecular probes to study biological pathways and protein interactions.
• Advanced Material Synthesis: Potential intermediate in the synthesis of specialty polymers or organic electronic materials requiring precise molecular architecture.

Basic Information

Product Name	4-(Piperazine-1-Carbonyl)-Benzoic Acid
CAS No.	691394-20-4
Molecular Formula	C12H14N2O3
Molecular Weight	234.25 g/mol
Synonyms	4-(Piperazine-1-carbonyl)benzoic acid; 4-(Piperazinecarbonyl)benzoic Acid; 4-(1-Piperazinylcarbonyl)benzoic Acid; Benzoic acid, 4-(1-piperazinylcarbonyl)-; 4-Carboxybenzoylpiperazine; 1-(4-Carboxybenzoyl)piperazine; 4-(Piperazine-1-ylcarbonyl)benzoic Acid; 691394-20-4
EINECS	Contact for details

Quality Control

Our 4-(Piperazine-1-Carbonyl)-Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.