Description

3-(Piperazine-1-Carbonyl)-Benzoic Acid is a high-purity organic building block featuring a benzoic acid core linked to a piperazine moiety via a carbonyl group. This molecular architecture makes it a versatile intermediate for synthesizing complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for creating novel active pharmaceutical ingredients (APIs) and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold or a critical fragment in the research and process chemistry stages of new API development.
• Bioconjugation and Probe Synthesis: Used in medicinal chemistry to create chemical probes, linkers, or tagged molecules for biological studies and diagnostic applications.
• Agrochemical Research: Employed as an intermediate in the development of new crop protection agents and herbicides.
• Material Science: Potential use as a monomer or cross-linking agent in the synthesis of specialized polymers with unique properties.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting synthetic organic chemistry and medicinal chemistry projects.

Basic Information

Product Name	3-(Piperazine-1-Carbonyl)-Benzoic Acid
CAS No.	691394-19-1
Molecular Formula	C12H14N2O3
Molecular Weight	234.25 g/mol
Synonyms	3-(Piperazine-1-carbonyl)benzoic acid; Benzoic acid, 3-(1-piperazinylcarbonyl)-; 3-(Piperazinecarbonyl)benzoic Acid; m-(Piperazine-1-carbonyl)benzoic Acid; 3-Carboxybenzoylpiperazine; 1-(3-Carboxybenzoyl)piperazine; 691394-19-1 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 3-(Piperazine-1-Carbonyl)-Benzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.