Description

2-Piperazinecarboxylicacid,5-(1-Methylethyl)-,(2S,5S)-(9Ci) is a high-purity, stereochemically defined piperazine derivative serving as a critical chiral building block in advanced organic synthesis. Its precise stereochemistry and functional groups make it an invaluable intermediate for constructing complex molecular architectures with high enantiomeric purity. This compound is primarily sought after by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and antiviral applications.
• Asymmetric Synthesis: Used as a ligand or precursor for chiral catalysts and auxiliaries in stereoselective chemical transformations.
• Peptidomimetics & Constrained Peptides: Incorporated into peptide backbones to induce specific conformational restraints and enhance metabolic stability.
• Agrochemical Research: Serves as a building block for developing novel, enantiomerically pure pesticides and herbicides.
• Material Science: Potential monomer or modifier in the synthesis of specialized polymers with unique properties.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	2-Piperazinecarboxylicacid,5-(1-Methylethyl)-,(2S,5S)-(9Ci)
CAS No.	687624-52-8
Molecular Formula	C8H16N2O2
Molecular Weight	172.23 g/mol
Synonyms	(2S,5S)-5-Isopropylpiperazine-2-carboxylic acid; (2S,5S)-5-(1-Methylethyl)-2-piperazinecarboxylic acid; (2S,5S)-5-Isopropyl-2-piperazinecarboxylic acid; L-5-Isopropylpiperazine-2-carboxylic acid (stereospecific); cis-5-Isopropylpiperazine-2-carboxylic acid; (2S,5S)-5-(Propan-2-yl)piperazine-2-carboxylic acid; 687624-52-8; UNII-Contact for details
EINECS	Contact for details

Quality Control

Every batch of (2S,5S)-5-Isopropylpiperazine-2-carboxylic acid is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high standards required for pharmaceutical and fine chemical applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as chiral purity (enantiomeric excess), chemical purity (HPLC), and residual solvent content.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged operations to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.