Description

3H-1,2,4-Triazol-3-One, 2-[(1S,2S)-1-Ethyl-2-Hydroxypropyl]-2,4-Dihydro-4-[4-[4-(4-Hydroxyphenyl)-1-Piperazinyl]Phenyl]- is a complex, high-purity chiral triazole derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated pharmaceutical intermediate or research chemical for developing novel active pharmaceutical ingredients (APIs) with specific stereochemistry. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring specific receptor binding profiles.
• Chemical Research & Development: Used as a precursor or model compound in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Process Chemistry: Serves as a critical chiral intermediate in the scale-up and optimization of synthetic routes for complex molecules.
• Biochemical Research: Potential use as a tool compound or ligand in biochemical assays and enzymatic studies due to its piperazinyl and hydroxyphenyl moieties.
• Fine Chemical Synthesis: Employed in the custom synthesis of specialty chemicals, agrochemicals, or advanced materials requiring precise molecular architecture.

Basic Information

Item	Details
Product Name	3H-1,2,4-Triazol-3-One, 2-[(1S,2S)-1-Ethyl-2-Hydroxypropyl]-2,4-Dihydro-4-[4-[4-(4-Hydroxyphenyl)-1-Piperazinyl]Phenyl]-
CAS No.	687132-01-0
Molecular Formula	C23H29N5O3
Molecular Weight	423.51 g/mol
Synonyms	2-[(1S,2S)-1-Ethyl-2-hydroxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one; (1S,2S)-1-Ethyl-2-hydroxypropyl triazolone derivative; 4-[4-[4-(4-Hydroxyphenyl)-1-piperazinyl]phenyl]-2-[(1S,2S)-1-ethyl-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one; CAS 687132-01-0; Hydroxyphenylpiperazinyl phenyl triazolone
EINECS	Contact for details

Quality Control

Our 3H-1,2,4-Triazol-3-One derivative is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% de
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.