Description

tert-Butyl 4-sec-Butylpiperazine-1-carboxylate is a high-purity, protected piperazine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for medicinal chemistry research and pharmaceutical development, offering a versatile scaffold for constructing complex molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drug candidates.
• Medicinal Chemistry Scaffold: Used in hit-to-lead optimization and library synthesis for drug discovery programs targeting G-protein coupled receptors (GPCRs) and kinases.
• Agrochemical Synthesis: Serves as a building block for developing novel fungicides, herbicides, and plant growth regulators.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes under cGMP conditions.
• Academic & Industrial Research: Used in universities and corporate R&D labs for exploring new chemical entities and reaction methodologies.

Basic Information

Product Name	tert-Butyl 4-sec-Butylpiperazine-1-carboxylate
CAS No.	686721-28-8
Molecular Formula	C13H26N2O2
Molecular Weight	242.36 g/mol
Synonyms	1-Boc-4-(sec-butyl)piperazine; 4-(sec-Butyl)piperazine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(1-methylpropyl)piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-sec-butylpiperazine; Boc-4-sec-butylpiperazine; N-Boc-4-(sec-butyl)piperazine; 686721-28-8; Piperazine, 4-(1-methylpropyl)-, 1-(1,1-dimethylethyl) ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-sec-Butylpiperazine-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, supporting development under ISO and cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.