Description

4-Cbz-1-Methyl-2-Piperazinone CAS NO 685520-31-4 is a high-purity, protected piperazinone derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a versatile, nitrogen-containing scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), especially within the fields of central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs.
• Peptidomimetic Research: Used to create constrained peptide analogs and protease inhibitors due to its piperazinone core.
• Chemical Library Synthesis: Employed in combinatorial and parallel synthesis to generate diverse compound libraries for high-throughput screening.
• Process Chemistry Development: Serves as a starting material or intermediate in the scale-up and optimization of API manufacturing routes.
• Academic & Contract Research: Utilized in university and CRO settings for fundamental research in heterocyclic and synthetic organic chemistry.

Basic Information

Product Name	4-Cbz-1-Methyl-2-Piperazinone
CAS No.	685520-31-4
Molecular Formula	C13H16N2O3
Molecular Weight	248.28 g/mol
Synonyms	1-Methyl-4-(benzyloxycarbonyl)-2-piperazinone; 4-(Benzyloxycarbonyl)-1-methyl-2-piperazinone; 4-Carbobenzoxy-1-methyl-2-piperazinone; 4-Cbz-1-Methylpiperazin-2-one; N1-Methyl-N4-Cbz-piperazin-2-one; Benzyl 1-methyl-2-oxopiperazine-4-carboxylate; 685520-31-4
EINECS	Contact for details

Quality Control

Our 4-Cbz-1-Methyl-2-Piperazinone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including HPLC, NMR, and mass spectrometry. We are committed to meeting the stringent requirements of our global clientele in the pharmaceutical and fine chemical sectors.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.