Description

n-(3-Oxo-3,4-Dihydro-2H-1,4-Benzoxazin-6-Yl)-4-(2-Pyridinyl)Tetrahydro-1(2H)-Pyrazinecarboxamide CAS NO 685107-80-6 is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel, high-value active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

This specialized intermediate is designed for sophisticated chemical synthesis in regulated environments. Its primary applications include:

• Pharmaceutical Intermediate: Serving as a crucial precursor in the multi-step synthesis of novel drug candidates, particularly for central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Enabling structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Reference Standard: Acting as a high-purity analytical standard for method development and quality control of final APIs.
• Contract Research & Manufacturing (CRAM): Supplying organizations that provide custom synthesis and development services to the pharmaceutical industry.

Basic Information

Product Name	n-(3-Oxo-3,4-Dihydro-2H-1,4-Benzoxazin-6-Yl)-4-(2-Pyridinyl)Tetrahydro-1(2H)-Pyrazinecarboxamide
CAS No.	685107-80-6
Molecular Formula	C₁₈H₁₉N₅O₃
Molecular Weight	353.38 g/mol
Synonyms	4-(Pyridin-2-yl)-N-(3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)piperazine-1-carboxamide; 6-({[4-(2-Pyridinyl)-1-piperazinyl]carbonyl}amino)-2H-1,4-benzoxazin-3(4H)-one; UNII-7V2P8U96QN; 7V2P8U96QN; BDBM50111625; ZINC000003869756; AKOS015915006; CHEMBL3183083
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation and residual solvent analysis to ensure it meets the exacting standards required for pharmaceutical R&D and manufacturing. Comprehensive Certificates of Analysis (COA) with full traceability are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.