Description

4-Benzothiazole-2-Yl-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate of significant commercial importance. This compound serves as a critical building block in the synthesis of complex molecules, particularly for active pharmaceutical ingredients (APIs) targeting neurological and oncological pathways. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of novel therapeutics.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those with benzothiazole and piperazine pharmacophores.
• Active Pharmaceutical Ingredient (API) Development: Used in research and scale-up for developing APIs targeting central nervous system (CNS) disorders.
• Oncology Research: Serves as a scaffold for developing potential anticancer agents due to the biological activity of the benzothiazole moiety.
• Contract Manufacturing: Supplied to CDMOs for custom synthesis and process development under cGMP conditions.
• Biochemical Research: Utilized in academic and industrial labs for studying enzyme inhibition and receptor binding activities.
• Chemical Reference Standard: Sourced for analytical method development, validation, and quality control in pharmaceutical analysis.

Basic Information

Product Name	4-Benzothiazole-2-Yl-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	684217-29-6
Molecular Formula	C17H23N3O2S
Molecular Weight	333.45 g/mol
Synonyms	tert-Butyl 4-(benzothiazol-2-yl)piperazine-1-carboxylate; 2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)benzothiazole; 1-Boc-4-(2-benzothiazolyl)piperazine; 4-(Benzothiazol-2-yl)-1-piperazinecarboxylic acid tert-butyl ester; N-Boc-4-(2-benzothiazolyl)piperazine; 1-(tert-Butoxycarbonyl)-4-(2-benzothiazolyl)piperazine; BOC-2-Benzothiazolylpiperazine
EINECS	Contact for details

Quality Control

Our 4-Benzothiazole-2-Yl-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for each lot. We support development and commercial projects with material suitable for research use and can supply grades aligned with cGMP guidelines for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.