Description

4-(Piperazin-1-Yl)Thieno[3,2-D]Pyrimidine CAS NO 683274-67-1 is a heterocyclic organic compound featuring a fused thienopyrimidine core substituted with a piperazine moiety, serving as a crucial advanced pharmaceutical intermediate. Its molecular architecture makes it a valuable building block for medicinal chemistry research and the synthesis of bioactive molecules. This compound is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates targeting various diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Kinase Inhibitor Development: Core scaffold for the research and development of small molecule kinase inhibitors due to the thienopyrimidine pharmacophore.
• Chemical Biology Probes: Utilized in the creation of molecular probes to study biological pathways and protein functions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development pipelines.
• Academic Research: Employed in university and institutional labs for exploratory synthetic chemistry and bioactivity screening.

Basic Information

Product Name	4-(Piperazin-1-Yl)Thieno[3,2-D]Pyrimidine
CAS No.	683274-67-1
Molecular Formula	C10H11N5S
Molecular Weight	233.29 g/mol
Synonyms	4-(1-Piperazinyl)thieno[3,2-d]pyrimidine; Thieno[3,2-d]pyrimidine, 4-(1-piperazinyl)-; 4-Piperazin-1-ylthieno[3,2-d]pyrimidine; 4-(Piperazin-1-yl)thieno[3,2-d]pyrimidine; 683274-67-1; AKOS025311317; BDBM50389375; ZINC000003870756; AS-15711; STL511602
EINECS	Contact for details

Quality Control

Every batch of 4-(Piperazin-1-Yl)Thieno[3,2-D]Pyrimidine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to support research and development requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.