Description

Piperazine, 2,3,5-Trimethyl-, (2R,3R,5R)-Rel- (9Ci) is a high-purity, stereochemically defined piperazine derivative that serves as a critical chiral building block in advanced organic synthesis. Its precise stereochemistry is essential for developing compounds with targeted biological activity, making it a valuable asset for research and development. This intermediate is primarily needed by pharmaceutical and agrochemical R&D teams focused on creating novel active ingredients, particularly in the areas of asymmetric catalysis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in creating molecules with specific stereochemical requirements.
• Agrochemical Synthesis: Used in the development of advanced, stereoselective pesticides and herbicides where the three-dimensional structure impacts efficacy and environmental profile.
• Asymmetric Catalysis: Serves as a precursor or ligand in catalytic systems designed for enantioselective synthesis, crucial for producing single-isomer compounds.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies to explore new chemical spaces and improve drug candidate properties.
• Fine Chemical Production: Utilized in the custom synthesis of complex, high-value specialty chemicals for various industrial and research applications.

Basic Information

Product Name	Piperazine, 2,3,5-Trimethyl-, (2R,3R,5R)-Rel- (9Ci)
CAS No.	682735-24-6
Molecular Formula	C7H16N2
Molecular Weight	128.22 g/mol
Synonyms	(2R,3R,5R)-2,3,5-Trimethylpiperazine; rel-(2R,3R,5R)-2,3,5-Trimethylpiperazine; 2,3,5-Trimethylpiperazine (stereoisomer); 2,3,5-Trimethylpiperazine, (2R,3R,5R)-rel-; Piperazine, 2,3,5-trimethyl-, (2R,3R,5R)-rel-; Chiral Trimethylpiperazine; TMP Derivative
EINECS	Contact for details

Quality Control

Our Piperazine, 2,3,5-Trimethyl-, (2R,3R,5R)-Rel- (9Ci) is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including chiral HPLC and NMR, to confirm identity, stereochemical purity, and chemical composition. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.