Description

Cyclopropanecarboxaldehyde, 2-Bromo-3-Methyl-, (1R,2R,3R)-Rel- (9Ci) is a high-value, stereochemically defined chiral building block featuring a reactive aldehyde group and a bromine substituent on a cyclopropane ring. This compound matters for its ability to introduce complex, constrained three-dimensional structures into target molecules, which is critical for modulating biological activity and physical properties in advanced research. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in areas requiring rigid, three-dimensional scaffolds.
• Agrochemical Synthesis: Used in creating novel pesticides and herbicides where the cyclopropane moiety can enhance stability and bioactivity.
• Advanced Material Research: Serves as a precursor for specialty polymers or liquid crystals that benefit from its unique stereochemistry and functional groups.
• Asymmetric Catalysis & Ligand Development: Employed in the synthesis of complex chiral ligands or catalysts for stereoselective transformations.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme mechanisms or protein-ligand interactions due to its reactive handles.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	Cyclopropanecarboxaldehyde, 2-Bromo-3-Methyl-, (1R,2R,3R)-Rel- (9Ci)
CAS No.	681536-52-7
Molecular Formula	C6H9BrO
Molecular Weight	177.04 g/mol
Synonyms	(1R,2R,3R)-2-Bromo-3-methylcyclopropanecarboxaldehyde; rel-(1R,2R,3R)-2-Bromo-3-methylcyclopropanecarbaldehyde; 2-Bromo-3-methylcyclopropanecarboxaldehyde (rel-(1R,2R,3R)-); (1R,2R,3R)-rel-2-Bromo-3-methylcyclopropanecarbaldehyde; Bromomethylcyclopropanecarboxaldehyde isomer
EINECS	Contact for details

Quality Control

Every batch of Cyclopropanecarboxaldehyde, 2-Bromo-3-Methyl-, (1R,2R,3R)-Rel- (9Ci) is produced and controlled under a strict quality management system. Our products undergo rigorous quality testing, including chiral purity analysis, to ensure compliance with exacting research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and stereochemical composition is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (rel-(1R,2R,3R)-)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.