Description

Benzamide, 3-[[4-[[(1R)-2,2-Dimethyl-1-(5-Methyl-2-Furanyl)Propyl]Amino]-1,1-Dioxido-1,2,5-Thiadiazol-3-Yl]Amino]-2-Hydroxy-N,N,6-Trimethyl- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters as a critical building block in the synthesis of novel therapeutic agents, offering researchers and manufacturers a reliable, high-quality starting material for complex organic transformations. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new drug candidates, particularly in areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and development of new active pharmaceutical ingredients (APIs), especially for targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its unique benzamide and thiadiazole dioxide motifs.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses requiring chiral, functionalized intermediates for constructing novel heterocyclic compounds.
• Biochemical Research: Potential use as a tool compound or probe in biochemical assays to study specific enzyme interactions or biological pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.

Basic Information

Product Name	Benzamide, 3-[[4-[[(1R)-2,2-Dimethyl-1-(5-Methyl-2-Furanyl)Propyl]Amino]-1,1-Dioxido-1,2,5-Thiadiazol-3-Yl]Amino]-2-Hydroxy-N,N,6-Trimethyl-
CAS No.	681514-83-0
Molecular Formula	C22H31N5O5S
Molecular Weight	477.58 g/mol
Synonyms	3-[[4-[[(1R)-2,2-Dimethyl-1-(5-methyl-2-furanyl)propyl]amino]-1,1-dioxido-1,2,5-thiadiazol-3-yl]amino]-2-hydroxy-N,N,6-trimethylbenzamide; (R)-3-((4-((2,2-Dimethyl-1-(5-methylfuran-2-yl)propyl)amino)-1,1-dioxido-1,2,5-thiadiazol-3-yl)amino)-2-hydroxy-N,N,6-trimethylbenzamide; Benzamide derivative (681514-83-0); 1,2,5-Thiadiazole 1,1-dioxide benzamide derivative; Advanced Pharmaceutical Intermediate 681514-83-0
EINECS	Contact for details

Quality Control

Our Benzamide, 3-[[4-[[(1R)-2,2-Dimethyl-1-(5-Methyl-2-Furanyl)Propyl]Amino]-1,1-Dioxido-1,2,5-Thiadiazol-3-Yl]Amino]-2-Hydroxy-N,N,6-Trimethyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects with quality standards tailored to your phase, from research use to cGMP.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to protect the compound from moisture. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.