Description

tert-Butyl 4-(4-Hydroxybenzoyl)Piperazine-1-Carboxylate is a high-purity, protected piperazine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, offering a reactive scaffold for further functionalization. Pharmaceutical R&D laboratories, agrochemical manufacturers, and specialty chemical producers need this material for creating novel compounds with potential therapeutic or functional properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging the piperazine core for biological activity.
• Chemical Synthesis Building Block: Employed in academic and industrial research for constructing diverse chemical libraries via amide bond formation and other reactions.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and metal complexation.
• Material Science Applications: Potential use in the synthesis of monomers or additives for advanced polymers and functional materials.

Basic Information

Item	Detail
Product Name	tert-Butyl 4-(4-Hydroxybenzoyl)Piperazine-1-Carboxylate
CAS No.	681482-86-0
Molecular Formula	C16H22N2O4
Molecular Weight	306.36 g/mol
Synonyms	1-Boc-4-(4-hydroxybenzoyl)piperazine; tert-Butyl 4-(4-hydroxybenzoyl)-1-piperazinecarboxylate; 4-(4-Hydroxybenzoyl)piperazine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(4-hydroxybenzoyl)piperazine; Boc-4-(4-hydroxybenzoyl)piperazine; N-Boc-4-(4-hydroxybenzoyl)piperazine; 681482-86-0; 4-Hydroxybenzoylpiperazine Boc-protected
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(4-Hydroxybenzoyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.