Description

2-Cyclopropyl-5,6,7,8-Tetrahydro-[1,2,4]Triazolo[1,5-A]Pyrazine CAS NO 681249-78-5 is a high-purity, advanced pharmaceutical intermediate belonging to the fused triazolopyrazine class of heterocyclic compounds. Its unique bicyclic structure, featuring both triazole and piperazine motifs, makes it a critical building block for medicinal chemistry research and the synthesis of novel active pharmaceutical ingredients (APIs). This compound is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing next-generation therapeutics, particularly in central nervous system (CNS) and oncology targets.

Application

This specialized intermediate serves as a key precursor in sophisticated organic synthesis. Its primary applications include:

• Pharmaceutical Intermediate: Core scaffold for the research and development of new drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for high-throughput screening.
• API Synthesis: A crucial building block in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs), especially in neurological and psychiatric disorders.
• Chemical Biology Probes: Serves as a starting material for creating tool compounds used to study biological processes and identify new drug targets.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	2-Cyclopropyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyrazine
CAS No.	681249-78-5
Molecular Formula	C8H12N4
Molecular Weight	164.21 g/mol
Synonyms	2-Cyclopropyl-5,6,7,8-tetrahydro[1,2,4]triazolo[1,5-a]pyrazine; 2-Cyclopropyl-4,5,6,7-tetrahydro-2H-[1,2,4]triazolo[1,5-a]pyrazine; [1,2,4]Triazolo[1,5-a]pyrazine, 2-cyclopropyl-5,6,7,8-tetrahydro-; 681249-78-5; 2-Cyclopropyl-2,4,5,6,7,8-hexahydro-[1,2,4]triazolo[1,5-a]pyrazine
EINECS	Contact for details

Quality Control

Our production of 2-Cyclopropyl-5,6,7,8-Tetrahydro-[1,2,4]Triazolo[1,5-A]Pyrazine adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee full traceability and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.