Description

2-Cyclopropyl-5,6,7,8-Tetrahydro-[1,2,4]Triazolo[1,5-A]Pyrazine is a high-purity, advanced pharmaceutical intermediate belonging to the fused triazolopyrazine class of heterocyclic compounds. Its value lies in its role as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. This compound is essential for medicinal chemistry research and development teams in the pharmaceutical and biotechnology industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization studies to explore structure-activity relationships (SAR) due to its unique fused bicyclic scaffold.
• API Development: Serves as a core structural motif in the development of new Active Pharmaceutical Ingredients (APIs) for clinical trials.
• Biochemical Tool Compound: Can be utilized in biochemical assays to study specific enzyme or receptor interactions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for pharmaceutical clients.
• Academic Research: Employed in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	2-Cyclopropyl-5,6,7,8-Tetrahydro-[1,2,4]Triazolo[1,5-A]Pyrazine
CAS No.	681249-77-4
Molecular Formula	C8H12N4
Molecular Weight	164.21 g/mol
Synonyms	2-Cyclopropyl-5,6,7,8-tetrahydro[1,2,4]triazolo[1,5-a]pyrazine; 2-Cyclopropyl-4,5,6,7-tetrahydro[1,2,4]triazolo[1,5-a]pyrazine; 681249-77-4; 2-cyclopropyl-4,5,6,7-tetrahydro-1,2,4-triazolo[1,5-a]pyrazine; AKOS025247317; CS-0446646; FT-0696055; NS-00068725; SCHEMBL18824027; 2-cyclopropyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyrazine
EINECS	Contact for details

Quality Control

Our 2-Cyclopropyl-5,6,7,8-Tetrahydro-[1,2,4]Triazolo[1,5-A]Pyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing batch-specific results are available upon request, providing full traceability and quality assurance for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.