Description

4-(3-Amino-Propionyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, protected piperazine derivative that serves as a critical building block in modern organic synthesis. This compound is essential for researchers and manufacturers requiring a versatile intermediate with orthogonal protecting groups for the selective construction of complex molecules. It is primarily utilized in the pharmaceutical and agrochemical industries for the development of new active ingredients, particularly in medicinal chemistry programs targeting novel therapeutics.

Application

• Pharmaceutical Intermediate: Key synthon for the development of small molecule drugs, particularly in creating piperazine-based pharmacophores.
• Medicinal Chemistry Research: Used in parallel synthesis and combinatorial chemistry for lead optimization and structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Building block for novel crop protection agents and pesticides.
• Peptidomimetics: Integral component in the design and synthesis of peptide mimics and constrained analogs.
• Chemical Biology Probes: Useful for creating tagged or functionalized molecules for studying biological pathways.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs for client-specific projects.

Basic Information

Product Name	4-(3-Amino-Propionyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	681248-23-7
Molecular Formula	C12H23N3O3
Molecular Weight	257.33 g/mol
Synonyms	1-Boc-4-(3-aminopropionyl)piperazine; tert-Butyl 4-(3-aminopropanoyl)piperazine-1-carboxylate; 4-(3-Aminopropanoyl)piperazine-1-carboxylic acid tert-butyl ester; N-Boc-4-(3-aminopropionyl)piperazine; 1-(tert-Butoxycarbonyl)-4-(3-aminopropionyl)piperazine; Piperazine-1-carboxylic acid, 4-(3-aminopropionyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 4-(3-Amino-Propionyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.