Description

1-(4-Bromo-Phenyl)-4-Isobutyl-Piperazine is a high-purity, functionalized piperazine derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research and development teams, process chemists, and manufacturers within the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate its unique bromo-phenyl and isobutyl-piperazine motifs into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the piperazine pharmacophore.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the bromine atom offers a site for further functionalization.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Precursor: Employed in the synthesis of monomers or additives for advanced polymers with specific thermal or mechanical properties.
• Chemical Biology Probe Synthesis: Utilized to build molecular tools for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	1-(4-Bromo-Phenyl)-4-Isobutyl-Piperazine
CAS No.	678996-44-6
Molecular Formula	C14H21BrN2
Molecular Weight	297.24 g/mol
Synonyms	4-(4-Bromophenyl)-1-(2-methylpropyl)piperazine; 1-(4-Bromophenyl)-4-(2-methylpropyl)piperazine; 4-Isobutyl-1-(4-bromophenyl)piperazine; N-(4-Bromophenyl)-N'-(2-methylpropyl)piperazine; 1-(p-Bromophenyl)-4-isobutylpiperazine; 4-Bromo-N-(4-isobutylpiperazin-1-yl)aniline
EINECS	Contact for details

Quality Control

Every batch of 1-(4-Bromo-Phenyl)-4-Isobutyl-Piperazine is manufactured and tested under a strict quality management system. We guarantee high chemical purity and consistency, supported by comprehensive analytical documentation. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to ensure compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.