Description

2-Piperazineacetamide, 5-(Mercaptomethyl)-3,6-Dioxo- (9Ci) is a specialized heterocyclic compound featuring a piperazine backbone integrated with a mercaptomethyl group and dioxo functionality. This unique molecular architecture makes it a valuable high-purity building block for advanced chemical synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and complex organic molecules. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new therapeutic agents, particularly those targeting neurological or metabolic pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in drug discovery programs, enabling structure-activity relationship (SAR) studies.
• Peptidomimetic Synthesis: Used in the design and synthesis of peptide analogs and mimetics due to its amide and heterocyclic structure.
• Ligand and Chelator Development: The mercapto (thiol) group provides a site for metal coordination, making it useful in developing chelating agents or catalysts.
• Bioconjugation Chemistry: The reactive thiol moiety allows for site-specific conjugation to proteins, antibodies, or other biomolecules in biopharmaceutical applications.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to introduce complex piperazine-based motifs into target molecules.

Basic Information

Product Name	2-Piperazineacetamide, 5-(Mercaptomethyl)-3,6-Dioxo- (9Ci)
CAS No.	677021-08-8
Molecular Formula	C7H11N3O3S
Molecular Weight	217.24 g/mol
Synonyms	5-(Mercaptomethyl)-3,6-dioxo-2-piperazineacetamide; 2-Piperazineacetamide, 5-(mercaptomethyl)-3,6-dioxo-; 5-(Mercaptomethyl)-3,6-dioxopiperazine-2-acetamide; (5-(Mercaptomethyl)-3,6-dioxopiperazin-2-yl)acetamide; CAS 677021-08-8
EINECS	Contact for details

Quality Control

Our production of 2-Piperazineacetamide, 5-(Mercaptomethyl)-3,6-Dioxo- (9Ci) adheres to stringent quality protocols suitable for research and pharmaceutical intermediate applications. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are provided and can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.