Description

2,5-Piperazinedione, 3-(Hydroxymethyl)-6-[2-(Methylthio)Ethyl]- (9Ci) is a specialized heterocyclic compound featuring a piperazinedione core with hydroxymethyl and methylthioethyl substituents, serving as a key advanced intermediate in modern synthetic chemistry. Its molecular architecture makes it a valuable building block for the development of novel pharmacologically active compounds, particularly in the research and synthesis of complex molecules. This high-purity intermediate is primarily targeted at pharmaceutical R&D laboratories and fine chemical manufacturers engaged in creating new therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting neurological or metabolic pathways.
• Peptidomimetic Research: Used in the design and construction of peptidomimetics and constrained peptide analogs due to its piperazinedione scaffold.
• Medicinal Chemistry: Serves as a versatile synthon for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals for agrochemical or material science applications.
• Bioconjugation Chemistry: The hydroxymethyl group can be utilized for linker attachment in the development of antibody-drug conjugates (ADCs) or other bioconjugates.
• Academic Research: A valuable compound for universities and research institutes studying heterocyclic chemistry and new synthetic methodologies.

Basic Information

Item	Details
Product Name	2,5-Piperazinedione, 3-(Hydroxymethyl)-6-[2-(Methylthio)Ethyl]- (9Ci)
CAS No.	677021-07-7
Molecular Formula	C8H14N2O3S
Molecular Weight	218.27 g/mol
Synonyms	3-(Hydroxymethyl)-6-(2-(methylthio)ethyl)piperazine-2,5-dione; 3-(Hydroxymethyl)-6-[2-(methylthio)ethyl]-2,5-piperazinedione; 6-[2-(Methylsulfanyl)ethyl]-3-(hydroxymethyl)piperazine-2,5-dione; 3-(Hydroxymethyl)-6-(2-methylthioethyl)-2,5-diketopiperazine; 2,5-Diketopiperazine derivative; DKP intermediate; (9CI) 677021-07-7
EINECS	Contact for details

Quality Control

Our 2,5-Piperazinedione, 3-(Hydroxymethyl)-6-[2-(Methylthio)Ethyl]- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and MS, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with complete chromatographic data and spectral references are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if possible to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.