Description

1-Palmitoyl-2-Oleoyl-3-Arachidonoyl-Rac-Glycerol is a chemically defined triacylglycerol (TAG) with a specific fatty acid composition at the sn-1, sn-2, and sn-3 positions. This structured lipid is of significant interest for advanced biochemical and pharmaceutical research, serving as a critical standard and substrate. It is primarily utilized by researchers and developers in the life sciences, particularly for studying lipid metabolism, membrane biophysics, and as a precursor for specialized lipid-based formulations.

Application

• Biochemical Research Standard: Used as a high-purity reference compound for the analysis and quantification of complex lipids in biological samples via techniques like LC-MS.
• Lipidomics & Metabolomics: Serves as a critical standard for calibrating instruments and validating methods in the study of cellular lipid profiles and metabolic pathways.
• Cell Membrane & Biophysics Studies: Employed in model membrane systems (e.g., liposomes, bilayers) to investigate the effects of specific fatty acid chains on membrane fluidity, permeability, and protein-lipid interactions.
• Pharmaceutical Excipient Development: Acts as a structured lipid component in the design and development of advanced drug delivery systems, such as lipid nanoparticles (LNPs) and self-emulsifying drug delivery systems (SEDDS).
• Enzyme Substrate: Used as a specific substrate for lipases, phospholipases, and other lipid-modifying enzymes to study enzyme kinetics, specificity, and inhibition.
• Nutritional Science Research: Investigated for its metabolic fate and potential bioactive effects in models of human nutrition and disease.

Basic Information

Product Name	1-Palmitoyl-2-Oleoyl-3-Arachidonoyl-Rac-Glycerol
CAS No.	675876-04-7
Molecular Formula	C₅₇H₁₀₀O₆
Molecular Weight	881.4 g/mol
Synonyms	POAr; 1-Palmitoyl-2-oleoyl-3-arachidonoyl-rac-glycerol; Glycerol 1-palmitate 2-oleate 3-arachidonate; rac-POAr; TAG(16:0/18:1/20:4); Triacylglycerol (16:0/18:1 n-9/20:4 n-6); 1-Hexadecanoyl-2-(9Z-octadecenoyl)-3-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-rac-glycerol
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as purity (by HPLC), identity confirmation (by NMR and/or MS), and fatty acid composition verification. We adhere to strict quality management protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen), as the compound is easily oxidized. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Fatty Acid Composition (GC)	Conforms to specified ratio
Peroxide Value	< 5.0 mEq/kg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.