Description

4-Methyl-2-Pyrrolidin-1-Ylmethyl-Piperazine-1-Carboxylic Acid Benzyl Ester is a sophisticated piperazine derivative and a key chiral building block in advanced organic synthesis. This compound matters for its role as a crucial intermediate in the development of active pharmaceutical ingredients (APIs), particularly for complex therapeutic agents. Pharmaceutical R&D teams and fine chemical manufacturers need it to construct novel molecular architectures with high stereochemical purity and functionality.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs), especially in central nervous system (CNS) and antiviral drug research.
• Asymmetric Synthesis: Utilized as a ligand or precursor in catalytic systems for asymmetric transformations, enabling the production of enantiomerically pure compounds.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Peptidomimetics Development: Used in the design and synthesis of peptidomimetic compounds, which mimic peptides but with improved stability and bioavailability.
• Custom Synthesis & Contract Manufacturing: A key starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke fine chemicals for client projects.
• Agrochemical Research: Potential intermediate in the development of advanced, targeted agrochemicals requiring specific chiral centers for biological activity.

Basic Information

Product Name	4-Methyl-2-Pyrrolidin-1-Ylmethyl-Piperazine-1-Carboxylic Acid Benzyl Ester
CAS No.	675602-56-9
Molecular Formula	C19H29N3O2
Molecular Weight	331.46 g/mol
Synonyms	Benzyl 4-methyl-2-[(pyrrolidin-1-yl)methyl]piperazine-1-carboxylate; 1-Carbobenzoxy-4-methyl-2-(pyrrolidin-1-ylmethyl)piperazine; 4-Methyl-2-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylic acid benzyl ester; (2S)-4-Methyl-2-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylic acid benzyl ester (for chiral form); 1-CBZ-4-Methyl-2-(N-pyrrolidinylmethyl)piperazine; Piperazine-1-carboxylic acid, 4-methyl-2-(1-pyrrolidinylmethyl)-, phenylmethyl ester
EINECS	Contact for details

Quality Control

Our 4-Methyl-2-Pyrrolidin-1-Ylmethyl-Piperazine-1-Carboxylic Acid Benzyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for specified enantiomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.