Description

Piperazinone, 3,5-Diethyl-, (3R,5R)- (9Ci) is a chiral, stereochemically defined piperazinone derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of novel pharmaceutical agents and bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of complex, stereoselective compounds, particularly for drug discovery and process chemistry applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic areas.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in stereoselective synthesis to introduce the (3R,5R)- configuration into target molecules.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis or as a scaffold for novel organocatalysts.
• Medicinal Chemistry Research: Serves as a core structural motif for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	Piperazinone, 3,5-Diethyl-, (3R,5R)- (9Ci)
CAS No.	674792-17-7
Molecular Formula	C8H16N2O
Molecular Weight	156.23 g/mol
Synonyms	(3R,5R)-3,5-Diethylpiperazin-2-one; (3R,5R)-3,5-Diethyl-2-piperazinone; (3R,5R)-3,5-Diethylpiperazinone; (3R,5R)-3,5-Diethyl-1,4-diazinan-2-one; (3R,5R)-3,5-Diethyl-2-ketopiperazine; (R,R)-3,5-Diethylpiperazin-2-one; 3,5-Diethyl-2-piperazinone, (3R,5R)-
EINECS	Contact for details

Quality Control

Our Piperazinone, 3,5-Diethyl-, (3R,5R)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.