Description

1-Boc-2,2-Dimethyl-Piperazine is a high-purity, protected piperazine derivative widely used as a critical building block in advanced organic synthesis. Its primary value lies in its role as a versatile intermediate for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working in pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for API synthesis and novel compound libraries.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Protecting Group Strategy: The tert-butoxycarbonyl (Boc) group provides orthogonal protection for the secondary amine, enabling selective reactions in multi-step synthetic sequences.
• Ligand and Catalyst Synthesis: Used to prepare sophisticated ligands for asymmetric catalysis and metal complexes.
• Peptidomimetic & Scaffold Development: Integral for creating constrained peptide analogs and diverse heterocyclic scaffolds in drug discovery programs.
• Agrochemical Research: Intermediate in the development of novel crop protection agents and pesticides.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for custom synthesis projects and scale-up activities.

Basic Information

Product Name	1-Boc-2,2-Dimethyl-Piperazine
CAS No.	674792-07-5
Molecular Formula	C11H22N2O2
Molecular Weight	214.31 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-2,2-dimethylpiperazine; 2,2-Dimethylpiperazine-1-carboxylic acid tert-butyl ester; tert-Butyl 2,2-dimethylpiperazine-1-carboxylate; N-Boc-2,2-dimethylpiperazine; Boc-2,2-dimethylpiperazine; 1-Boc-2,2-dimethylpiperazine; 2,2-Dimethyl-1-N-Boc-piperazine
EINECS	Contact for details

Quality Control

Our 1-Boc-2,2-Dimethyl-Piperazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC analysis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.