Description

(S)-1-n-Boc-Isobutylpiperazine is a high-purity, chiral piperazine derivative used as a critical building block in advanced organic synthesis. This compound is essential for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, offering a versatile scaffold for medicinal chemistry. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Peptidomimetic Chemistry: Serves as a constrained dipeptide surrogate or a conformational constraint element in peptide-based drug design.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis and organometallic complexes.
• Agrochemical Synthesis: An intermediate in the production of advanced, biologically active crop protection agents.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring high enantiomeric purity.
• Academic & Industrial R&D: Employed in exploratory chemistry for developing new chemical entities and libraries for screening.

Basic Information

Product Name	(S)-1-n-Boc-Isobutylpiperazine
CAS No.	674792-06-4
Molecular Formula	C13H26N2O2
Molecular Weight	242.36 g/mol
Synonyms	(S)-1-(tert-Butoxycarbonyl)-4-isobutylpiperazine; (S)-1-Boc-4-isobutylpiperazine; (S)-4-Isobutyl-1-piperazinecarboxylic acid tert-butyl ester; (S)-N-Boc-4-isobutylpiperazine; tert-Butyl (S)-4-isobutylpiperazine-1-carboxylate; (S)-1-N-Boc-4-isobutylpiperazine; (S)-1-(tert-Butoxycarbonyl)-4-(2-methylpropyl)piperazine
EINECS	Contact for details

Quality Control

Our (S)-1-n-Boc-Isobutylpiperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity, to ensure it meets the high standards required for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.