Description

(R)-2-Isopropyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-purity chiral piperazine derivative, serving as a critical building block in modern asymmetric synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules with high enantiomeric purity. This advanced pharmaceutical intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Asymmetric Catalyst Ligand Precursor: Used to develop sophisticated chiral ligands for transition metal catalysis, enabling enantioselective transformations.
• Agrochemical Synthesis: Employed in the research and production of enantiomerically pure agrochemicals for enhanced efficacy and environmental profile.
• Custom Chemical Synthesis: Serves as a versatile starting material for contract research organizations (CROs) and CDMOs for custom synthesis projects.
• Academic & Industrial Research: A valuable reagent for methodological development in organic and medicinal chemistry research laboratories.

Basic Information

Product Name	(R)-2-Isopropyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	674792-04-2
Molecular Formula	C12H24N2O2
Molecular Weight	228.33 g/mol
Synonyms	(R)-1-Boc-2-isopropylpiperazine; (R)-N-Boc-2-isopropylpiperazine; tert-Butyl (R)-2-(propan-2-yl)piperazine-1-carboxylate; (R)-2-Isopropyl-1-(tert-butoxycarbonyl)piperazine; (R)-1-(tert-Butoxycarbonyl)-2-isopropylpiperazine; (R)-N-tert-Butoxycarbonyl-2-isopropylpiperazine; (R)-2-(1-Methylethyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; Boc-(R)-2-isopropylpiperazine
EINECS	Contact for details

Quality Control

Our (R)-2-Isopropyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.