Description

1H-Indene-4-Carboxaldehyde,Octahydro-3A-Hydroxy-7A-Methyl-1-Oxo-,(3Ar,4S,7Ar)-Rel-(9Ci) is a high-purity, stereochemically defined synthetic intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key chiral building block, enabling the construction of complex molecular architectures with precise three-dimensional control. It is primarily needed by research and development teams in the pharmaceutical and fine chemical industries for applications in medicinal chemistry, process development, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and development of new therapeutic agents, particularly for complex small-molecule drugs.
• Asymmetric Synthesis: Utilized as a building block in stereoselective reactions to introduce specific chiral centers into target molecules.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies to explore novel chemical space.
• Process Chemistry Development: Used in scaling up synthetic routes for potential Active Pharmaceutical Ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Fine Chemical Synthesis: Acts as a precursor for the manufacture of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and catalysis within university and corporate laboratories.

Basic Information

Product Name	1H-Indene-4-Carboxaldehyde,Octahydro-3A-Hydroxy-7A-Methyl-1-Oxo-,(3Ar,4S,7Ar)-Rel-(9Ci)
CAS No.	674347-84-3
Molecular Formula	C11H16O3
Molecular Weight	196.24 g/mol
Synonyms	(3aR,4S,7aR)-Octahydro-3a-hydroxy-7a-methyl-1-oxo-1H-indene-4-carboxaldehyde; Rel-(3aR,4S,7aR)-Octahydro-3a-hydroxy-7a-methyl-1-oxo-1H-indene-4-carbaldehyde; 1-Oxo-octahydro-3a-hydroxy-7a-methyl-1H-indene-4-carboxaldehyde; Chiral Indane Aldehyde Derivative; (3aR,4S,7aR)-4-Formyl-3a-hydroxy-7a-methyl-octahydroinden-1-one
EINECS	Contact for details

Quality Control

Our 1H-Indene-4-Carboxaldehyde,Octahydro-3A-Hydroxy-7A-Methyl-1-Oxo-,(3Ar,4S,7Ar)-Rel-(9Ci) is manufactured under strict quality systems to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical characterization, including chiral purity assessment, to meet the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.