Description

Piperazine, 1-[(2-Ethyl-4-Methyl-1H-Imidazol-5-Yl)Methyl]-4-[4-(Trifluoromethyl)-2-Pyridinyl]- is a specialized heterocyclic organic compound that serves as a high-value pharmaceutical intermediate and research chemical. Its unique molecular architecture, featuring a piperazine core linked to substituted imidazole and pyridine rings, makes it a critical building block for the synthesis of novel bioactive molecules. This compound is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Biochemical Tool Compound: Serves as a ligand or inhibitor in pharmacological assays to study specific biological pathways.
• Fine Chemical Synthesis: Building block for creating complex molecules with potential agrochemical or material science applications.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name	Piperazine, 1-[(2-Ethyl-4-Methyl-1H-Imidazol-5-Yl)Methyl]-4-[4-(Trifluoromethyl)-2-Pyridinyl]-
CAS No.	674292-58-1
Molecular Formula	C19H22F3N5
Molecular Weight	377.41 g/mol
Synonyms	1-[(2-Ethyl-4-methyl-1H-imidazol-5-yl)methyl]-4-[4-(trifluoromethyl)pyridin-2-yl]piperazine; 4-[4-(Trifluoromethyl)pyridin-2-yl]-1-[(2-ethyl-4-methyl-1H-imidazol-5-yl)methyl]piperazine; 674292-58-1; UNII-8J4L8G3J6F; 8J4L8G3J6F; CHEMBL3186662; ZINC000006544008; AKOS009158947
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.