Description

1-(n-Methyl-n-Boc-Glycinyl)Piperazine is a high-purity, protected amino acid derivative used as a critical building block in advanced organic synthesis. This compound is essential for the controlled introduction of a piperazine moiety with a protected glycine unit, enabling the synthesis of complex molecules with precise structural control. It is primarily utilized by research and development chemists in the pharmaceutical and biotechnology sectors for creating novel active pharmaceutical ingredients (APIs), peptide mimetics, and other sophisticated chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Peptide Chemistry: Serves as a protected dipeptide-like building block for solid-phase and solution-phase peptide synthesis (SPPS).
• Chemical Biology Probes: Used in the design and synthesis of molecular probes for studying enzyme function and protein-protein interactions.
• Library Synthesis: A valuable reagent for generating diverse compound libraries in medicinal chemistry for high-throughput screening.
• Linker and Spacer Unit: Incorporated into the design of bioconjugates, antibody-drug conjugates (ADCs), and targeted delivery systems.
• Agrochemical Research: Employed in the synthesis of novel compounds for crop protection and agricultural science research.

Basic Information

Product Name	1-(n-Methyl-n-Boc-Glycinyl)Piperazine
CAS No.	671212-37-6
Molecular Formula	C13H25N3O4
Molecular Weight	287.36 g/mol
Synonyms	1-[(2-{[(tert-Butoxy)carbonyl](methyl)amino}acetyl)]piperazine; N-Boc-N-methylglycylpiperazine; N-(tert-Butoxycarbonyl)-N-methylglycylpiperazine; 1-(N-Methyl-N-Boc-glycyl)piperazine; Boc-N-methyl-Gly-Pip; Boc-N-Me-Gly-Pip-OH; (tert-Butoxycarbonylmethylamino)acetic acid piperazide; 2-[(tert-Butoxycarbonyl)(methyl)amino]-1-(piperazin-1-yl)ethan-1-one
EINECS	Contact for details

Quality Control

Our 1-(n-Methyl-n-Boc-Glycinyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the stringent requirements for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.