Description

Bicyclo[4.1.0]Heptane-7-Carboxylic Acid, 7-Amino-, Methyl Ester, (1R,6S)-Rel- (9Ci) is a high-purity, stereochemically defined bicyclic amino acid ester building block. This compound is valued for its rigid, fused-ring structure which is instrumental in the design and synthesis of novel, conformationally restricted pharmacophores. It is a critical intermediate for research and development chemists working in advanced pharmaceutical synthesis, agrochemical discovery, and materials science. The precise stereochemistry and functional groups make it a versatile precursor for creating complex molecules with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug discovery programs.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides where a rigid, bicyclic scaffold can enhance binding affinity and environmental stability.
• Peptidomimetics & Constrained Peptides: Serves as a non-natural amino acid analog to introduce conformational constraints into peptide chains, improving metabolic stability and receptor selectivity.
• Ligand & Catalyst Development: Employed in the creation of chiral ligands for asymmetric catalysis and organometallic complexes.
• Material Science Precursor: Potential monomer or cross-linking agent for synthesizing specialty polymers with unique thermal or mechanical properties.
• Chemical Biology Probes: Useful for constructing molecular probes to study enzyme mechanisms or protein-protein interactions.

Basic Information

Product Name	Bicyclo[4.1.0]Heptane-7-Carboxylic Acid, 7-Amino-, Methyl Ester, (1R,6S)-Rel- (9Ci)
CAS No.	669773-94-8
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	(1R,6S)-rel-7-Aminobicyclo[4.1.0]heptane-7-carboxylic acid methyl ester; Methyl (1R,6S)-rel-7-aminobicyclo[4.1.0]heptane-7-carboxylate; 7-Azabicyclo[4.1.0]heptane-7-carboxylic acid, methyl ester, (1R,6S)-rel-; Amino Bicycloheptane Carboxylate Methyl Ester; Bicyclo[4.1.0]heptane-7-carboxylic acid, 7-amino-, methyl ester, rel-(1R,6S)-; 669773-94-8; (1R,6S)-7-Amino-7-methoxycarbonylbicyclo[4.1.0]heptane
EINECS	Contact for details

Quality Control

Every batch of our Bicyclo[4.1.0]Heptane-7-Carboxylic Acid, 7-Amino-, Methyl Ester is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. Certificates of Analysis (COA) detailing identity, purity (typically by HPLC or GC), chiral purity, and impurity profiles are available for all shipments. Our quality protocols are designed to support cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.