Description

5-[[4-[2-[5-Ethyl-6-[4-[2-(5-Ethylpyridin-2-Yl)Ethoxy]Phenyl]Pyridin-2-Yl]Ethoxy]Phenyl]Methyl]-1,3-Thiazolidine-2,4-Dione is a high-purity, non-sulfonylurea thiazolidinedione derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and study of novel therapeutic agents targeting metabolic disorders. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing next-generation treatments.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel thiazolidinedione-based drug candidates.
• Research Chemical: Reference standard and active material for in-vitro and in-vivo pharmacological studies, particularly in metabolic disease research.
• Biochemical Tool: Used to investigate mechanisms of action related to peroxisome proliferator-activated receptor (PPAR) modulation.
• Process Development: Serves as a critical material for scaling up synthetic routes and optimizing manufacturing processes under GMP conditions.
• Analytical Standard: High-purity grade for use in method development, validation, and quality control testing in analytical laboratories.

Basic Information

Item	Detail
Product Name	5-[[4-[2-[5-Ethyl-6-[4-[2-(5-Ethylpyridin-2-Yl)Ethoxy]Phenyl]Pyridin-2-Yl]Ethoxy]Phenyl]Methyl]-1,3-Thiazolidine-2,4-Dione
CAS No.	669716-56-7
Molecular Formula	C35H35N3O4S
Molecular Weight	593.74 g/mol
Synonyms	5-[[4-[2-[5-Ethyl-6-[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]-2-pyridinyl]ethoxy]phenyl]methyl]-2,4-thiazolidinedione; GSK199; GSK-199; 5-[[4-[2-[5-Ethyl-6-[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]pyridin-2-yl]ethoxy]phenyl]methyl]thiazolidine-2,4-dione; GSK 199; 2,4-Thiazolidinedione, 5-[[4-[2-[5-ethyl-6-[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]-2-pyridinyl]ethoxy]phenyl]methyl]-
EINECS	Contact for details

Quality Control

Our 5-[[4-[2-[5-Ethyl-6-[4-[2-(5-Ethylpyridin-2-Yl)Ethoxy]Phenyl]Pyridin-2-Yl]Ethoxy]Phenyl]Methyl]-1,3-Thiazolidine-2,4-Dione is produced under a strict quality management system. Each batch undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request. We support development and commercial projects requiring compliance with ICH guidelines and can provide material suitable for use under GMP conditions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.