Description

2H-Pyran, Tetrahydro-2-[(28-Phenyl-3,6,9,12,15,18,21,24,27-Nonaoxaoctacos-1-Yl)Oxy]- is a specialized functionalized tetrahydropyran derivative featuring a long-chain polyethylene glycol (PEG) spacer terminated with a phenyl group. This compound matters as a high-value chemical building block and linker molecule, prized for its ability to impart solubility, modify hydrophilicity, and act as a spacer in complex syntheses. It is primarily needed by researchers and manufacturers in the pharmaceutical, bioconjugation, and advanced materials sectors for developing drug delivery systems, prodrugs, and functional polymers.

Application

• Pharmaceutical Intermediate: Used in the synthesis of prodrugs and active pharmaceutical ingredients (APIs) requiring PEGylation for enhanced solubility and pharmacokinetics.
• Bioconjugation Linker: Serves as a heterobifunctional crosslinker for attaching drugs, dyes, or other molecules to proteins, antibodies, or nanoparticles.
• Polymer Chemistry: Acts as a functional monomer or chain transfer agent in the synthesis of stimuli-responsive or amphiphilic block copolymers.
• Surface Modification: Employed to create hydrophilic, non-fouling coatings on medical devices or sensor surfaces via the reactive tetrahydropyran group.
• Material Science: Utilized in the development of hydrogels, dendrimers, and other advanced materials where controlled spacing and solubility are critical.
• Chemical Biology Probes: Functions as a key component in the design of probes for studying biological processes, leveraging its linker properties.

Basic Information

Item	Details
Product Name	2H-Pyran, Tetrahydro-2-[(28-Phenyl-3,6,9,12,15,18,21,24,27-Nonaoxaoctacos-1-Yl)Oxy]-
CAS No.	669556-53-0
Molecular Formula	C39H70O11
Molecular Weight	714.97 g/mol
Synonyms	2-[(28-Phenyl-3,6,9,12,15,18,21,24,27-nonaoxaoctacos-1-yl)oxy]tetrahydro-2H-pyran; THP-PEG9-Ph; Tetrahydropyranyl-PEG9-phenyl ether; PEG9 phenyl tetrahydropyranyl ether; 3,6,9,12,15,18,21,24,27-Nonaoxaoctacosan-1-yl phenyl ether, 2-tetrahydropyranyl derivative; Phenyl-PEG9-THP; Heterobifunctional PEG linker THP-PEG9-Ph
EINECS	Contact for details

Quality Control

Our 2H-Pyran, Tetrahydro-2-[(28-Phenyl-3,6,9,12,15,18,21,24,27-Nonaoxaoctacos-1-Yl)Oxy]- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture uptake. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.