Description

2-(1-Piperazinyl)Acetic Acid Monohydrate is a versatile piperazine derivative, a key building block in organic synthesis and pharmaceutical research. Its value lies in its bifunctional structure, featuring both a reactive carboxylic acid group and a piperazine ring, enabling its use as a crucial intermediate for creating complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries, particularly for developing new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Ligand Synthesis: Used in the preparation of chelating agents and ligands for catalysis and metal complexation studies.
• Agrochemical Development: Serves as a precursor in the research and production of advanced pesticides and herbicides.
• Bioconjugation Chemistry: The carboxylic acid group facilitates coupling reactions for labeling proteins, peptides, and other biomolecules.
• Polymer Modification: Employed to introduce functional piperazine groups into polymer chains, altering material properties.
• Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways and chemical entities.

Basic Information

Product Name	2-(1-Piperazinyl)Acetic Acid Monohydrate
CAS No.	667462-09-1
Molecular Formula	C6H12N2O2 • H2O
Molecular Weight	162.18 g/mol (Anhydrous basis)
Synonyms	2-(Piperazin-1-yl)acetic acid monohydrate; 1-Piperazineacetic acid monohydrate; (Piperazin-1-yl)acetic acid hydrate; Piperazine-1-acetic acid monohydrate; 2-Piperazin-1-ylacetic acid hydrate; NSC 169102 (monohydrate); UNII-7G1J5Z431G (monohydrate form)
EINECS	Contact for details

Quality Control

Our 2-(1-Piperazinyl)Acetic Acid Monohydrate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, KF for water content, and identity confirmation (IR, NMR) to ensure it meets exacting standards for research and production use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent absorption of atmospheric moisture, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	10.0% - 12.0% (Theoretical: ~11.1%)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.