Description

Mizagliflozin CAS NO 666843-10-3 is a potent and selective sodium-glucose cotransporter 2 (SGLT2) inhibitor. This compound is of significant interest for its role in the research and development of novel therapeutic agents targeting metabolic disorders. It is primarily utilized by pharmaceutical research organizations and fine chemical manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs). The demand for high-purity Mizagliflozin is driven by its critical application in preclinical and clinical studies for diabetes management.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of SGLT2 inhibitor drug candidates.
• Biochemical Research: Used as a reference standard and tool compound for studying glucose reabsorption mechanisms in renal physiology.
• Drug Discovery & Development: Essential for in-vitro and in-vivo pharmacological screening and efficacy studies for type 2 diabetes treatments.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the production of finished dosage forms under controlled GMP environments.
• Metabolic Disorder Studies: Applied in academic and industrial research to investigate new pathways for managing hyperglycemia and related complications.

Basic Information

Item	Detail
Product Name	Mizagliflozin
CAS No.	666843-10-3
Molecular Formula	C23H25ClO6
Molecular Weight	432.90 g/mol
Synonyms	Mizagliflozin; (1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol; KGA-2727; SGLT2 Inhibitor KGA-2727; 1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol; (1S)-1,5-Anhydro-1-C-[3-[(4-ethoxyphenyl)methyl]-4-chlorophenyl]-D-glucitol
EINECS	Contact for details

Quality Control

Our Mizagliflozin is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Maximum Impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.