Description

4-[2-(4-Methoxy-Phenyl)-2-Oxo-Ethyl]-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, protected piperazine derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring a ketone linker and a Boc-protected piperazine, makes it an invaluable intermediate for constructing complex pharmacophores. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Peptidomimetic Synthesis: Used to introduce constrained piperazine scaffolds into peptide backbones to enhance metabolic stability and receptor binding affinity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying enzyme mechanisms and protein-protein interactions.
• Agrochemical Research: Acts as an intermediate in the discovery of new crop protection agents and herbicides.
• Material Science: Potential monomer or cross-linker in the development of specialty polymers with specific functional properties.

Basic Information

Product Name	4-[2-(4-Methoxy-Phenyl)-2-Oxo-Ethyl]-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	664362-19-0
Molecular Formula	C18H26N2O4
Molecular Weight	334.41 g/mol
Synonyms	tert-Butyl 4-[2-(4-methoxyphenyl)-2-oxoethyl]piperazine-1-carboxylate; 1-Boc-4-(2-(4-methoxyphenyl)-2-oxoethyl)piperazine; 4-(2-(4-Methoxyphenyl)-2-oxoethyl)piperazine-1-carboxylic acid tert-butyl ester; N-Boc-4-(2-(4-methoxyphenyl)-2-oxoethyl)piperazine; 1-(tert-Butoxycarbonyl)-4-[2-(4-methoxyphenyl)-2-oxoethyl]piperazine; 664362-19-0; BOC-Piperazine-(4-methoxyphenacyl)
EINECS	Contact for details

Quality Control

Our 4-[2-(4-Methoxy-Phenyl)-2-Oxo-Ethyl]-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with REACH and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.