Description

2,5-Piperazinedione, 3-(Methoxymethyl)-, (3R)- (9Ci) is a chiral piperazinedione derivative, a sophisticated building block of significant interest in advanced organic synthesis. Its value lies in its stereochemically defined structure, which is crucial for constructing complex molecules with high enantiomeric purity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and oncology targets.
• Asymmetric Synthesis: Serves as a precursor or scaffold for constructing complex, enantiomerically pure molecules in medicinal chemistry programs.
• Peptidomimetic Research: Used in the design and synthesis of peptidomimetics, where the piperazinedione core mimics peptide bonds and influences secondary structure.
• Chemical Biology Probes: Employed in the creation of specialized probes and ligands for studying enzyme mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis organizations (CSOs) producing high-value, low-volume compounds for clients.
• Academic Research: Utilized in university and institutional labs for methodological development in organic chemistry and catalysis studies.

Basic Information

Product Name	2,5-Piperazinedione, 3-(Methoxymethyl)-, (3R)- (9Ci)
CAS No.	660862-80-6
Molecular Formula	C7H12N2O3
Molecular Weight	172.18 g/mol
Synonyms	(3R)-3-(Methoxymethyl)piperazine-2,5-dione; (R)-3-(Methoxymethyl)-2,5-piperazinedione; (R)-3-(Methoxymethyl)diketopiperazine; 3-(Methoxymethyl)-2,5-diketopiperazine, (R)-; (R)-3-Methoxymethyl-2,5-diketopiperazine; (R)-3-Methoxymethyl-DKP; (R)-MMDKP; (R)-3-(Methoxymethyl)-2,5-dioxopiperazine
EINECS	Contact for details

Quality Control

Our production of (R)-3-(Methoxymethyl)piperazine-2,5-dione adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical R&D. All materials are characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.