Description

(S)-N4-Benzyl-2-(Methylthioethyl)Piperazine is a high-purity chiral piperazine derivative of significant interest in advanced pharmaceutical synthesis. This compound serves as a critical chiral building block and intermediate for the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and process development of new therapeutic agents, particularly those targeting the central nervous system.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for neurological and psychiatric applications.
• Asymmetric Synthesis: Used as a chiral ligand or auxiliary in catalytic asymmetric reactions to induce stereoselectivity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs due to its defined stereochemistry and functional groups.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and commercial route development for complex target molecules.
• Chemical Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(S)-N4-Benzyl-2-(Methylthioethyl)Piperazine
CAS No.	660862-41-9
Molecular Formula	C14H22N2S
Molecular Weight	250.40 g/mol
Synonyms	(S)-1-Benzyl-2-(2-(methylthio)ethyl)piperazine; (S)-N-Benzyl-2-(2-(methylthio)ethyl)piperazine; (S)-2-(2-(Methylthio)ethyl)-1-(phenylmethyl)piperazine; (S)-1-(Benzyl)-2-(2-(methylthio)ethyl)piperazine; (S)-N-Benzyl-2-(methylthioethyl)piperazine; (S)-2-(Methylthioethyl)-N-benzylpiperazine; (S)-Benzyl(methylthioethyl)piperazine
EINECS	Contact for details

Quality Control

Our (S)-N4-Benzyl-2-(Methylthioethyl)Piperazine is manufactured under strict quality management systems. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing chiral purity, chemical purity (typically >97% by HPLC), and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.