Description

3,4-Piperidinediol, 5-Methyl-1-(Phenylmethyl)-, (3R,4R)-Rel- (9Ci) is a high-purity, stereochemically defined piperidine derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and synthetic intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex molecules with potential therapeutic applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to explore novel chemical space.
• Process Chemistry: Serves as a starting material or intermediate in the scalable synthesis of target molecules under Good Manufacturing Practice (GMP) conditions.
• Asymmetric Synthesis: Exploited for its defined stereochemistry in catalytic and stoichiometric asymmetric transformations to construct complex chiral architectures.
• Fine Chemical Synthesis: Employed in the production of specialty chemicals, agrochemicals, and advanced materials requiring high stereochemical purity.
• Academic & Contract Research: A valuable reagent for universities and contract research organizations (CROs) conducting synthetic methodology development.

Basic Information

Product Name	3,4-Piperidinediol, 5-Methyl-1-(Phenylmethyl)-, (3R,4R)-Rel- (9Ci)
CAS No.	660403-89-4
Molecular Formula	C13H19NO2
Molecular Weight	221.30 g/mol
Synonyms	rel-(3R,4R)-5-Methyl-1-benzylpiperidine-3,4-diol; (3R,4R)-5-Methyl-1-(phenylmethyl)-3,4-piperidinediol; 1-Benzyl-5-methyl-3,4-piperidinediol (rel-(3R,4R)-); 5-Methyl-1-benzyl-3,4-piperidinediol (rel-(3R,4R)-); (3R,4R)-rel-5-Methyl-1-benzylpiperidine-3,4-diol; 660403-89-4; Benzyl 5-methyl-3,4-piperidinediol (stereoisomer)
EINECS	Contact for details

Quality Control

Our 3,4-Piperidinediol, 5-Methyl-1-(Phenylmethyl)-, (3R,4R)-Rel- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and development applications. We provide comprehensive analytical data, including chiral purity and impurity profiles, via HPLC, NMR, and other spectroscopic techniques. A Certificate of Analysis (COA) detailing identity, purity, and specific tests is available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (diastereomeric excess)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.