Description

1-Methyl-3-Phenylpiperidine-4-Carboxylic Acid is a specialized piperidine derivative that serves as a high-value synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a carboxylic acid and a phenyl-substituted piperidine ring, makes it a critical building block for constructing complex molecular architectures. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of new therapeutic agents, particularly in central nervous system (CNS) and analgesic drug candidates.
• Organic Synthesis Building Block: Used to introduce the 1-methyl-3-phenylpiperidine moiety into more complex molecules for structure-activity relationship (SAR) studies.
• Chemical Research: Employed in academic and industrial laboratories for methodological development in heterocyclic and medicinal chemistry.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing chiral ligands or organocatalysts due to its potential for further functionalization.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	1-Methyl-3-Phenylpiperidine-4-Carboxylic Acid
CAS No.	658712-69-7
Molecular Formula	C13H17NO2
Molecular Weight	219.28 g/mol
Synonyms	4-Carboxy-1-methyl-3-phenylpiperidine; 3-Phenyl-1-methylpiperidine-4-carboxylic acid; 1-Methyl-3-phenyl-4-piperidinecarboxylic acid; 658712-69-7; 1-Methyl-3-phenylpiperidine-4-carboxylate (acid form)
EINECS	Contact for details

Quality Control

Our 1-Methyl-3-Phenylpiperidine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods (NMR, IR), to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for that lot.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.