Description

Pyrazinecarboxamide, 3-Amino-n-[(1R,2S)-2-Phenylcyclopropyl]-, Rel- (9Ci) is a high-purity, stereochemically defined pharmaceutical intermediate of significant commercial interest. This compound is valued for its role as a key building block in the synthesis of advanced active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring high stereochemical fidelity. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in the development of novel small-molecule drugs.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Chemical Synthesis: Used in advanced organic synthesis to introduce the 3-aminopyrazinecarboxamide moiety with specific stereochemistry into complex molecular architectures.
• Medicinal Chemistry Research: Serves as a valuable scaffold or precursor for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Development: Employed in the scale-up and optimization of synthetic routes for target molecules in pilot plant and commercial manufacturing settings.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in API production.

Basic Information

Product Name	Pyrazinecarboxamide, 3-Amino-n-[(1R,2S)-2-Phenylcyclopropyl]-, Rel- (9Ci)
CAS No.	658683-92-2
Molecular Formula	C14H16N4O
Molecular Weight	256.31 g/mol
Synonyms	rel-(1R,2S)-N-(2-Phenylcyclopropyl)-3-aminopyrazine-2-carboxamide; 3-Amino-N-[(1R,2S)-2-phenylcyclopropyl]pyrazine-2-carboxamide; (1R,2S)-2-Phenylcyclopropanamine derivative; 3-Aminopyrazine-2-carboxylic acid (1R,2S)-2-phenylcyclopropylamide; A chiral pyrazinecarboxamide intermediate
EINECS	Contact for details

Quality Control

Our production of Pyrazinecarboxamide, 3-Amino-n-[(1R,2S)-2-Phenylcyclopropyl]-, Rel- (9Ci) adheres to stringent quality management systems. Each batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and cGMP manufacturing needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storage under inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.