Description

1-Piperazinecarboxylicacid,2-Methyl-,Ethylester,(2S)-(9Ci) is a high-purity chiral piperazine derivative, a critical building block in modern synthetic chemistry. Its defined stereochemistry and functionalized structure make it an invaluable intermediate for constructing complex molecules with high enantiomeric purity. This compound is primarily sought after by pharmaceutical R&D and fine chemical synthesis teams for the development of new active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring specific chiral centers.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel drug candidates, including central nervous system (CNS) agents and protease inhibitors.
• Asymmetric Synthesis: Used as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Agrochemical Research: Building block for developing advanced, enantiomerically pure pesticides and herbicides.
• Peptidomimetics: Core scaffold for designing and synthesizing peptide mimics with enhanced metabolic stability and bioavailability.
• Chemical Biology Probes: Utilized in the creation of tagged molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds under cGMP or research-grade conditions.

Basic Information

Product Name	1-Piperazinecarboxylicacid,2-Methyl-,Ethylester,(2S)-(9Ci)
CAS No.	657427-69-5
Molecular Formula	C8H16N2O2
Molecular Weight	172.23 g/mol
Synonyms	(2S)-2-Methyl-1-piperazinecarboxylic acid ethyl ester; Ethyl (2S)-2-methylpiperazine-1-carboxylate; (S)-2-Methyl-1-piperazinecarboxylic acid ethyl ester; (S)-Ethyl 2-methylpiperazine-1-carboxylate; 1-Piperazinecarboxylic acid, 2-methyl-, ethyl ester, (2S)-; 657427-69-5; (S)-1-(Ethoxycarbonyl)-2-methylpiperazine; (2S)-2-Methylpiperazine-1-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 1-Piperazinecarboxylicacid,2-Methyl-,Ethylester,(2S)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.