Description

1-Piperazinecarboxylicacid,3-Methyl-,Ethylester,(3R)-(9Ci) is a chiral piperazine derivative and a key synthetic intermediate in advanced organic chemistry. This compound matters for its role as a critical building block in the development of active pharmaceutical ingredients (APIs) and fine chemicals, where stereochemical purity is paramount. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides requiring specific stereochemistry for efficacy.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: Employed in medicinal chemistry for creating peptide analogs and conformationally restricted scaffolds.
• Custom Synthesis Building Block: Provides a versatile, stereodefined core for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects.

Basic Information

Product Name	1-Piperazinecarboxylicacid,3-Methyl-,Ethylester,(3R)-(9Ci)
CAS No.	657424-03-8
Molecular Formula	C8H16N2O2
Molecular Weight	172.22 g/mol
Synonyms	(R)-3-Methylpiperazine-1-carboxylic acid ethyl ester; Ethyl (3R)-3-methylpiperazine-1-carboxylate; (R)-Ethyl 3-methylpiperazine-1-carboxylate; 1-Carbethoxy-3-methyl-(R)-piperazine; 1-Piperazinecarboxylic acid, 3-methyl-, ethyl ester, (3R)-; 657424-03-8; (R)-1-(Ethoxycarbonyl)-3-methylpiperazine
EINECS	Contact for details

Quality Control

Our 1-Piperazinecarboxylicacid,3-Methyl-,Ethylester,(3R)-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.