Description

4-(2-Bromoethyl)-1-Piperazinecarboxylic Acid, 1,1-Dimethylethyl Ester is a versatile and high-purity chemical building block, specifically a Boc-protected bromoethyl piperazine derivative, essential for advanced organic synthesis. Its primary value lies in providing a protected piperazine scaffold with a reactive bromoethyl handle, enabling precise and controlled molecular construction under mild conditions. This compound is critically needed by pharmaceutical R&D and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs), agrochemicals, and complex specialty molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• API Synthesis: Used in constructing complex molecular architectures for active pharmaceutical ingredients, leveraging the reactive bromoethyl group for further functionalization.
• Agrochemical Development: Serves as a precursor in the creation of advanced herbicides, fungicides, and insecticides.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands for metal catalysis or as a component in catalyst design.
• Peptidomimetic & Bioactive Compound Research: Employed in medicinal chemistry to create piperazine-containing peptidomimetics and other bioactive molecules.
• Custom Synthesis & Contract Manufacturing: A critical raw material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	4-(2-Bromoethyl)-1-Piperazinecarboxylic Acid, 1,1-Dimethylethyl Ester
CAS No.	655225-01-7
Molecular Formula	C11H21BrN2O2
Molecular Weight	293.20 g/mol
Synonyms	tert-Butyl 4-(2-bromoethyl)piperazine-1-carboxylate; 1-Boc-4-(2-bromoethyl)piperazine; N-Boc-4-(2-bromoethyl)piperazine; 1-(tert-Butoxycarbonyl)-4-(2-bromoethyl)piperazine; 4-(2-Bromoethyl)piperazine-1-carboxylic acid tert-butyl ester; Boc-4-(2-bromoethyl)piperazine; Piperazine, 4-(2-bromoethyl)-, 1-(1,1-dimethylethyl) 1-carbamate; 655225-01-7
EINECS	Contact for details

Quality Control

Our 4-(2-Bromoethyl)-1-Piperazinecarboxylic Acid, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and cGMP applications. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC, to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.